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Journal of Korean Neurosurgical Society 2001;30(10): 1245-1249.
Periventricular Germinoma.
Young Yi Kwon, Bong Jin Park, Jung Nam Sung, Young Joon Kim, Maeng Ki Cho
Departement of Neurosurgery, College of Medicine, Dankook University, Cheonan, Korea.
ABSTRACT
Germinomas of the central nervous system are rare embryonal tumors(accounting for less than 1% of intracranial neoplasms) that may be located in the pineal region, in the floor of the third ventricle, or in the suprasellar area. We report a case of germinoma developed in periventricular deep white matter without pineal region tumors or suprasellar masses. The 19-year-old male patient presented with slowly progressing headache, dizziness, photophobia, and dysarthria. Initial brain MRI revealed a irregular and dense enhancement from lateral ventricles to 4th ventricle. The stereotactic biopsy of tumor and histologic examination revealed the germinoma. Craniospinal axis radiation therapy was performed. After radiation therapy patient was improved and no neurologic sequelae was seen at discharge. Periventricular germinomas without pineal or suprasellar lesion are very rare. The radiation therapy, as in our case, is beneficial as with other intracranial germinomas. Stereotactic biopsy of periventricular germinoma provides precise pathologic diagnosis and thus allows more specific management.
Key Words: Germinoma; Periventricles; Stereotactic biopsy; Radiation therapy
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