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Journal of Korean Neurosurgical Society 1985;14(3): 519-526. |
Clinical Study on the Effect of TRH in Patients with Prolonged Mild Disturbance of Consciousness. |
Dae Hee Han, Hee Won Jung, Bo Sung Sim |
Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea. |
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ABSTRACT |
Authors report the clinical study on the usefulness of thyrotropin-releasing hormone tartrate(TRH-T) in the treatment of mild disturbance of consciousness. 20 patients suffering head trauma, subarachnoid hemorrhage, and intracerebral hemorrhage were given TRH-T intravenously for ten days. TRH-T was effective for the patients in whom the consciousness disturbance was mild, the duration in fixed consciousness level was short, and the brain was not distorted on CT scan. These features were most prominent in patients with subarachnoid hemorrhage. Three was no significant side effect, and TRH-T turned out to be safe. |
Key Words:
Thyrotropin-releasing hormone tartrate; Mild disturbance of consciousness; III-3 formula; Usefulness |
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