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Case Report
Journal of Korean Neurosurgical Society 1998;27(9): 1277-1282.
A Case of Adrenal Neuroblastoma Presented with Late Brain Metastasis.
Joo Yeon Cho, Jae Gon Moon, Choong Seon Yoo, Byung Chan Jeon, Han Kyu Kim, Hwa Dong Lee, Jae Sun Park
1Department of Neurosurgery, College of Medicine, Kosin University, Pusan, Korea.
2Department of Pediatrics, College of Medicine, Kosin University, Pusan, Korea.
ABSTRACT
Intracranial metastasis from primary extracranial neuroblastoma is rare and parenchymal involvement is even rarer. Its pathogenesis is uncertain and the outcomes from the previous reports during the past several decades indicate a uniformly poor. The operative findings of this case suggest that the neural crest derived tissues providing the appropriate "soil" to support CNS-metastasizing neuroblastoma. We report a case of cerebral metastatic neuroblastoma which has relapsed in adrenal gland and discuss its pathogenesis with review of the literature.
Key Words: Neuroblastoma; CNS metastasis; Pathogenesis; Adrenal gland
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