Primary Cerebellar Hodgkin's Lymphoma.

Hwang, Chul Yoon; Song, Young Jin; Kim, Dae Chul; Choi, Sun Seob; Choi, Young Min; Kim, Ki Uk

Case Report

Journal of Korean Neurosurgical Society 2007;42(2): 149-152.

Chul Yoon Hwang, Young Jin Song, Dae Chul Kim, Sun Seob Choi, Young Min Choi, Ki Uk Kim

¹Department of Neurosurgery, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea. kukim@donga.ac.kr
²Department of Pathology, College of Medicine, Brain Tumor Institute Dong-A University, Busan, Korea.
³Department of Diagnostic Radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.
⁴Department of Onco-radiology, Brain Tumor Institute College of Medicine, Dong-A University, Busan, Korea.

ABSTRACT

Authors report a very rare case of primary Hodgkin's lymphoma limited to the cerebellum. A 64-year-old female patient presented with headache, nausea, and vomiting. Magnetic resonance imaging of the brain revealed a nodular enhancing mass in the left cerebellar hemisphere. Tumor was removed totally with retromastoid suboccipital approach. Diagnosis was Hodgkin's lymphoma of mixed cellularity type, consisting of a dense mixed inflammatory infiltrate containing scattered large atypical mononuclear Hodgkin cells and multinucleated Reed-Sternberg cells. Systemic work-up for the Hodgkin's lymphoma was followed with negative result. Postoperative radiation therapy was given and the patient is disease-free at 16 months after the operation.