Erratum to “Retrospective Analysis of Cerebrospinal Fluid Profiles in 228 Patients with Leptomeningeal Carcinomatosis : Differences According to the Sampling Site, Symptoms, and Systemic Factors” by Shim Y, et al. (J Korean Neurosurg Soc 59 : 570–576, 2016)

Article information

J Korean Neurosurg Soc. 2018;61(2):287-288
Publication date (electronic) : 2018 February 28
doi : https://doi.org/10.3340/jkns.2016.59.6.570.e1

https://doi.org/10.3340/jkns.2016.59.6.570

In this article by Shim et al., the measurement unit of CSF cell count was given incorrectly. It should be “cells/mm3” instead of “cells/cm3”.

Corrected sentences are as follows;

Page 570 Results of abstract :

Cell counts (median : 8 vs. 1 cells/mm3) and protein levels (median : 68 vs. 17 mg/dL) significantly higher in lumbar CSF than in ventricular CSF (p<0.001).

Page 571 (right column), line 46–53 :

The mean total cell count in the lumbar CSF was 25.0 cells/mm3 (standard deviation : ±47.3; range : 0–310). The reference normal range was set at ≤5 cells/mm3. The distribution of the cell count had a leftward skew (median : 8 cells/mm3; third quartile : 25 cells/mm3) (Fig. 1A). The distribution of the cell counts in the ventricular CSF was also skewed (mean : 10.4 cells/mm3; standard deviation : ±44.2; range : 0–360; median : 1 cells/mm3; third quartile : 5 cells/mm3) (Fig. 1B).

Page 573 (left column) line 5 :

(median: 2 vs. 9 cells/mm3; p=0.046).

Page 574 (right column) line 1–2 :

the ventricular CSF (1 cell/mm3) was within the normal range and that 75% of the patients had ≤5 cells/mm3.

Page 574 Table 2 :

Lumbar and ventricular CSF profiles correlated with LMC symptoms (n=228)

Article information Continued

Table 2

Lumbar and ventricular CSF profiles correlated with LMC symptoms (n=228)

LMC symptoms Lumbar CSF profiles Ventricular CSF profiles


Cell count (cells/mm3) p value Protein (mg/dL) p value Cell count (cells/mm3) p value Protein (mg/dL) p value CEA (n=109) p value
Increased ICP (15 mm Hg) 0.57 0.34 0.47 0.50 0.40
 Yes (n=129) 7 (0–300) 75.5 (17–703) 1 (0–360) 18.5 (7–223) 53 (0–5098)
 No (n=99) 8 (0–205) 63 (17–1246) 1 (0–180) 17 (6–885) 13 (0–2822)
Hydrocephalus 0.62 0.049 0.58 0.15 0.01
 Yes (n=59) 9 (0–100) 92.5 (25–1064) 1 (0–180) 19 (6–885) 96 (0–4057)
 No (n=169) 8 (0–300) 61 (17–1246) 1 (0–360) 16 (6–237) 12 (0–5098)
Cauda equina syndrome 0.45 <0.001 0.34 0.11 0.56
 Yes (n=54) 8 (0–282) 118 (35–1246) 0 (0–90) 19 (6–114) 25.3 (0–4057)
 No (n=174) 8 (0–300) 59 (17–889) 1 (0–360) 16 (6–885) 15 (0–5098)
Cranial neuropathy 0.046 0.54 0.16 0.44
 Yes (n=23) 2 (0–175) 68 (17–1246) 0 (0–79) 0.16 16 (8–237) 0.44 8(0–2822) 0.72
 No (n=205) 9 (0–300) 61 (21–570) 1 (0–360) 17 (6–885) 20.8 (0–5098)

Representative numbers are median value and numbers in the parenthesis are ranges of observed values. CSF : cerebrospinal fluid, LMC : leptomeningeal carcinomatosis, ICP : intracranial pressure, CEA : carcinoembryonic antigen