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Journal of Korean Neurosurgical Society > Volume 5(2); 1976 > Article
Journal of Korean Neurosurgical Society 1976;5(2): 293-298.
A Case of Nonketotic Hyperglycemic Hyperosmolar Coma.
Kyung Soo Park, Jung Shick Ki, Bo Sung Sim
Department of Neurosurgery, College of Medicine, Seoul Nation University, Seoul, Korea.
The entity of nonketotic hyperglycemic hyperosmolar coma(NHHC) was described as a severe and often fatal complication in 1957 (Sament and Schwartz), but since then it has been observed as a complication of various primary diseases, both in diabetic and nondiabetic patients. Various predisposing factors in its development include administration of prolonged mannitol, steroid, Dilantin, hyperosmolar tube feeding, dehydration, and diabetes. Combination of these factors are frequently used I the management of patients with neurological disorders and cerebral edema, consequently, a higher prevalence of NHHC might be expected in these patients. We have recently experienced a case of typical NHHC, in whom treated by mannitol, steroid, and Dilantin after emergency craniotomy for head injury.
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