Prolactin-Secreting Adenoma.

Ha, Y S; Kang, J K; Huh, C W

Original Article

Journal of Korean Neurosurgical Society 1980;9(1): 51-54.

Department of Neurosurgery, Catholic Medical Center, Seoul, Korea.

ABSTRACT

Recently many reports have the trends to classify the pituitary tumors into active and inactive adenomas endocrinologically substituting the classic 3 types after the radioimmunoassay for pituitary hormones and an analysis of the ultrastructural structures of tumors are advanced. An amenorrhea-galactorrhea syndromes, of course, belongs to the prolactin-secreting adenoma. Authors has experienced 6 cases of prolactin-secreting adenoma, admitted to the Department of Neurosurgery of the Catholic Medical College from July 1976 to August 1979. They were a man of 34 years old with loss of libido, 3 women in 2nd decade and 2 women in 4th decade. 4 women presented with secondary amenorhea in duration of average 6 years and one of 22 years old had the primary amenorrhea and the galactorrhea. Level of their serum prolactin increased from 42 ng/ml to over 100 ng/ml. Additionally a 35 years man who were diagnosed the eosinophillic adenoma could subjected to growth hormone-prolactin secreating adenoma with 50 ng/ml of growth hormone and 62 ng/ml of serum prolactin.