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Journal of Korean Neurosurgical Society 1986;15(4): 671-680. |
A Clinical Study on 37 Cases of Oligodendroglioma. |
Ha Young Kim, Hee Won Jung, Byung Kyu Cho, Dae Hee Han, Je G Chi, Kil Soo Choi, Bo Sung Sim |
1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea. 2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea. |
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ABSTRACT |
The authors reviewed 37 consecutive cases of histologically proven oligodendroglioma who were treated at the Seoul National University Hospital, between 1979 and 1986. There was a 1.5 : 1 male to female ratio. The age of patients at the time of diagnosis varied between 6 and 64 years(mean 38 years), with 51% in the fourth and fifth decades. The incidence of oligodendrogliomas represented 5% of all brain tumors and 15.5% of all gliomas. All but one were located supratentorially and 54% of them involved the frontal lobe.
The mean duration of symptoms prior to the surgery was 27.2 months, but seizures had a considerably longer duration of 6.4 years. The common symptoms were headache(62%), seizures(38%), and motor weakness(22%). The common neurological findings were papilledema(51%), motor dificit(24%), and change in cognition(19%). Six out of 37 cases(16%) presented as the spontaneous intracranial hemorrhage. Calcifications were detected on plain X-ray films of the skull in 19% of patients and fine vascular stains were found on carotid angiograms in 30% of the cases.
Brain CT revealed calcification(57%), cyst formation(43%), low density(35%) and heterogenous contrast enhancement(35%).
The important factors affecting the prognosis and the recurrence rate were (1) the extent of surgical excision, (2) postoperative radiation therapy, and (3) the pathologic grading. There was a significant difference in the recurrence rate between patients treated with postoperative irradiation and patients treated with surgery alone. |
Key Words:
Cerebral glioma; Oligodendroglioma; Brain CR Recurrence rate; Radiation therapy; Pathologic grade |
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