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Journal of Korean Neurosurgical Society 1988;17(3): 477-486.
Significance of Single Photon Emission CT and Topographic EEG in Diagnosis of Patients with Various Kinds of Cerebral Lesion.
S H Kwon, H K Rha, G S Lee, M S Ahn, C R Choi, J U Song, S Y Lee
1Department of Neurosurgery, St, Paul's Hospital Catholic Medical College, Seoul, Korea.
2Department of Radiology, St, Paul's Hospital Catholic Medical College, Seoul, Korea.
Authors measured cerebral blood flow(CBF) with single photon emission computed tomography(SPECT) in 43 patients with various kinds of cerebral lesions and the finding of CBF was compared to those of CT scan and topographic EEG. Of 43 patients, 14 cases were cerebral vascular insufficiency, 6 were cerebral infarction, 4 intracerebral hematoma, 2 A-V malfromation, 1 moy moya disease, 8 brain contusion, 4 seizure disorder, 3 brain tumor, and one case was hydrocephalus. In measurement of rCBF, two dimensional method using radioactive isotope, Xe-133 or Kr-85 had several limitations. Recently a new radiopharmaceutical(Technetium HM-PAO), ideal for SPECT was reported. Therefore SPECT of three dimensional method was widely used in measurement of CBF. After advent of CT scan, clinical use of conventional EEG was less attention, but topographic representation of the EEG data was considered beneficial in correcting the previous problems in the conventional EEG. The results were as follows: 1) Of 43 patients with brain lesions, SPECT and topographic EEG were appeared to be better method than CT scan in the diagnosis and follow-up study in patients with cerebrovascular insufficiency, mild brain contusion and seizure disorder. 2) Seizure focus could be found on SPECT and topographic EEG in patient with focal seizure who was showed to be normal on CT scan of the brain. 3) SPECT and topographical EEG might be useful tools for the diagnosis and follow-up study in patients with functional derangement rather anatomical abnormality of the brain for example, repeated TIA, focal seizure, and dementia.
Key Words: Cerebral blood flow(CBF); Single photon emission computed tomography(SPECT); Topographic EEG; Technitium HMPAO
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