| Home | E-Submission | Sitemap | Editorial Office |  
top_img
Journal of Korean Neurosurgical Society 1988;17(4): 841-852.
A Case of Peripheral Neuroblastoma (Involing Skull).
Yang Wha Park, Ik Seung Kwon, Yeun Seuk Ryu, Mee Kyung Shin, Moon Bae Choi, Seung Kuan Hong, Myong Sun Moon
Department of Neurosurgery, Seoul Red Cross Hospital, Seoul, Korea.
ABSTRACT
The peripheral neuroblastomas are malignant neoplasms that originate from the adrenal gland and sympathetic nervous tissues. They usually occur in childhood. They exhibit such malignant features that they metastasize early to lung, liver, bone, rarely skull and other structures. The patients with peripheral neuroblastoma have short duration of symptom and short survival period. They reveal the characteristic light microscopic features that resemble other small cell carcinomas. The establishment of final diagnosis of peripheral neuroblastoma needs various special stainings for small cell carcinomas, and the electron microscopic findings are the most reliable. The authors recently experienced a case of peripheral neuroblastoma in a 26-year-old man which involved right frontoparietal skull vault. The only chief complaint was a local non-tender mass at right frontoparietal scalp. Neither headache nor any neurological deficits was detected. Simple skull X-ray revealed a punched out radiolucency at right frontoparietal bone and brain CT showed a superficial elliptical high density mass that enhanced strongly. The mass was totally removed by wide craniectomy. The tumor invaded and penetrated the dura but the arachnoid membrane. At the tumor bed was not invaded by the tumor. The tumor was confirmed as peripheral neuroblastoma by various special stainings for small cell carcinomas. Following surgical resection of the mass, post-operative radiotherapy was offered(4800 rads for about 5 weeks). The patient aggrevated progressively and showed numerous metastases to such bones as lumbar vertebrae, pelvis and humerus to became paraplegic. 8 months after the operation, the patient died.
Key Words: Peripheral neuroblastoma; Small cell carcinoma; Craniectomy; Radiotherapy; Metastasis; Prognosis in skull metastasis
TOOLS
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Share:      
METRICS
1,380
View
15
Download
Related articles
A Case of Ependymoblastoma.  1972 October;1(1)
A Case of Intramedullary Neurilemmoma.  1974 June;3(1)
A Case of Trigemjinal Neurinoma in Puberty.  1974 June;3(1)
A Case of the Metastatic Hepatocellular Hepatoma to the Skull.  1975 June;4(1)
A Case of Spontaneous Intracerebral Hematoma in Childhood.  1975 June;4(1)
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: office@jkns.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer