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Journal of Korean Neurosurgical Society 1989;18(4): 629-633.
Primary Intracranial Tumors of Different Histological Types(Multiple Primary Brain Tumors): Report of Two Cases.
Won Ho Kim, Won Han Shin, Young Tak Park, Soon Kwan Choi, Bark Jang Byun, In Soo Lee, Dong Wha Lee
1Department of Neurosurgery, College of Medicine, Soonchunhyang University, Seoul, Korea.
2Department of Pathology, College of Medicine, Soonchunhyang University, Seoul, Korea.
The presence of multiple, diverse primary brain tumors is infrequent in patients without phakomatosis. We wish to report two cases of multiple primary brain tumors. The first case, a 38-year-old female, suffered from headache, bilateral hearing loss for about 6 years prior to hospitalization. Camputed tomography scan demonstrated multiple well enhanced masses in the right frontal convexity, falx and both cerebellopontine angles. These lesions were removed successfully in 3 successive operations. Histologically the tumors were diagnosed as afibroblastic meningiomas and a acoustic neurinoma. Although none of the cutaneous stigmata of von Reck1inghausen's disease has been observed in her and any member of her family, we cant's exclude this case that belongs in the central form of neurofibromatosis. The 2nd case, a 71-year-old male, suffered from frontal headache with confusion for about 7 days prior to hospitalization. Computed tomography scan demonstrated a ring enhanced mass with surrounding edema in the left frontal lobe. The left frontal osteoplastic craniotomy was performed, a small mass with the dura attached could be found incidentally, and this small mass and the ring enhanced tumor in the frontal deep portion were grossly totally removed. Histologically the two tumors were dIagnosed as a menigotheliomatous meningioma and a malignant astrocytoma.
Key Words: Multiple primary brain tumors; Meningioma; Neurinoma; Malignant astrocytoma; Central neurofibromatosis
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