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Journal of Korean Neurosurgical Society 1989;18(7-12): 1098-1102.
Histiocytosis X with Involvement of Pituitary Stalk: Case Report.
Byung Kyu Cho, Kyu Chang Wang, Sei Won Yang, Je G Chi, In One Kim, Kil Soo Choi
1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
2Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea.
3Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
4Department of Diagnostic Radiology, College of Medicine, Seoul National University, Seoul, Korea.
A case of histiocytosis X with the involvement of pituitary stalk in a 5 year old boy was described. He presented with diabetes insipidus and the endocrinological study showed growth hormone deficiency. On computerized tomography and magnetic resonance imaging, the pituitary stalk was abnormally thick. Overlooking of the skull lesion on plain X-ray film led to an erroneous diagnosis of germ cell tumor'. Gross total removal of the lesion and chemotherapy were performed. In the differential diagnosis of suprasellar masses, this disease entity should be included. The importance of histological diagnosis of the infundibular lesion in cases of central diabetes insipidus is also emphasized.
Key Words: Histiocytosis X; Pituitary stalk; Diabetes insipidus; Growth hormone deficiency
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