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Journal of Korean Neurosurgical Society > Volume 21(7); 1992 > Article
Journal of Korean Neurosurgical Society 1992;21(7): 844-859.
The Clinical Experience of Gliosarcoma(3 Cases).
Chae Hyuk Lee, Chang Jin Kim, Yang Kwon, Seung Chul Rhim, Jung Kyo Lee, Byung Duk Kwun, C Jin Whang
Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
The clinicopathologic features of 3 cases of intracerebral gliosarcoma are reported and correlations among the CT findings, angiographic findings, the surgical and histological aspects are discussed. In two cases, these tumors appear on CT scan as an isodense mass with well defined margins and homogenous contrast enhancement, attached to flax, which may mimic that of meningioma, but has a cystic or necrotic area and calcific area. Angiographic findings are different, one showed scanty tumor staining and another showed mixed dural and pial vascular supply, early cortical venous drainage, irregular tumor vessels, and a prominent vascular stain with well defined tumor margins. These tumors were rather well demarcated, firm in surgical aspect. In order case, tumor appears on CT scan as huge intracerebral lesions, with large necrotic areas and peripheral contrast enhancement:this CT aspect, similar to that of glioblastoma, corresponds to a rather diffusely infiltrating growth of the tumor and the prevalence of a gliomatous component. The genesis and histopathology of gliosarcoma are also discussed and we needs more prolonged period of time for study on metastasis and prognosis of these cases.
Key Words: Angiography; Computed tomography; Glioblastoma; Gliosarcoma; Histopathology
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