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Journal of Korean Neurosurgical Society 1992;21(9): 1121-1128.
Regional Cerebral Blood Flow in Experimental Feline Hydrocephalus.
Joong Uhn Choi, Kyu Chang Lee, Seung Kon Huh, Hyung Chun Park, Seung Chul Lim, Seong Hoon Oh
Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea.
To evaluate the cerebral blood flow in feline hydrocephalic brain, this study was designed to measure the regional cerebral blood flow(rCBF;frontal and periventricular area) by the hydrogen clearance method in different stages of the kaolin-induced hydrocephalus and the postshunt status. The results were as follows: 1) A reduction of rCBF was detected in the left periventricular area at two weeks after kaolin injection. A significant reduction of rCBF was revealed in the left periventricular area at two and four weeks after kaolin injection. However, the rCBF of the left frontal cortex was significantly decreased at four weks after kaolin injection. 2) At one week after shunt operation, the significant restroration of rCBF was found in the left frontal cortex and the left periventricular area.
Key Words: Hydrocephalus; Shunt; CBF
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