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Journal of Korean Neurosurgical Society > Volume 22(11); 1993 > Article
Journal of Korean Neurosurgical Society 1993;22(11): 1175-1183.
Postoperative Intratumoral Injection of Bleomycin for Cystic Craniopharyngioma.
Soo Han Yoon, Joong Uhn Choi, Eun Young Kim
Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea.
Surgical excision or irradiation of craniopharyngioma is problematic because both are often associated with high risk of complications. Three cases of cystic craniopharyngioma were subtotally removed by surgery and followed by repeated injection of bleomycin into the remaining tumor cavity as postoperative adjuvant therapy. With bleomycin injection, tumors were shrunk postoperatively in two cases out of three ut in one case cyctic portion became increased in size progressively which needed second operation and irradiation. Bleomycin injection could be considered as one of the reasonable alternative adjuvant therapies for incompletely removed cystic craniopharyngioma before radiation therapy.
Key Words: Chemotherapy; Craniopharyngioma; Bleomycin; Local injection
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