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Journal of Korean Neurosurgical Society 1994;23(8): 982-989.
Clinical Experience of the Primitive Neuroectodermal Tumors.
Ho Kyu Jeon, Young Soo Ha, Chong Oon Park, Young Kim, Kweon Byeong Chae, Sang Don Lee, Jae Joong Kim, Tae Kyeong Jin
Department of Neurosurgery, School of Medicine, Inha University, Incheon, Korea.
ABSTRACT
Primitive neuroectodermal tumors(PNETs) are composed of undifferentiated cells resembling germinal matrix cells of the embryonic neural tube. The concept of the primitive neuroectodermal tumors is controversial due to indistinct clinicopathologic entities. While some neuropathologists believe that the PNET concept should be applied to all these tumors with the addition of qualifying terms, the opponents of this approach believe this concept to be too simplistic and that well-established diagnostic entities should not be grouped together as a single entity. Four patients with PNET were reviewed. Although the PNETs bear some differences to posterior fossa medulloblastomas, we should be grouped together as a single pathologic entity because of their primitive nature. The purpose of this study is to review the similarties and differences between two tumors from their histologic and embryologic features.
Key Words: Primitive neuroectodermal tumor; Medulloblastoma
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