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Journal of Korean Neurosurgical Society > Volume 23(12); 1994 > Article
Journal of Korean Neurosurgical Society 1994;23(12): 1454-1459.
A Case of Neurofibromatosis 2 with Multiple Intracranial and Intraspinal Tumors:Neurofibromatosis 2(NF2).
Chang Yeong Kwon, Nam Jung, Moon Soo Shin, Kwang Soo Lee, Sung Kon Huh, Jin Ock Choi, Hae Kung Lee
1Department of Neurosurgery, Presbyterian Medical Center, Chonju, Korea.
2Department of Radiology, Presbyterian Medical Center, Chonju, Korea.
3Department of Pathlogy, Presbyterian Medical Center, Chonju, Korea.
ABSTRACT
Neurofibromatosis 1(NF-1, Von Recklinghausen disease) and Neurofibromatosis 2(NF-2, bilateral acoustic neurinoma) have been established as distinct disorders by the National Institutes of Health(NIH) Consensus Development Conference in 1988. We recently have encountered a patient of NF-2 who develop multiple intracranial and spinal tumors 12 years after the surgical treatment of Schwannoma of lumbar nerve roots. The tumors were right acoustic neurinoma, left cerebellopontine angle(CPA) meningioma, multiple intracranial meningiomas, intraorbital glioma, multiple ependymomas of the brain stem and cervical spinal cord, and meningiomas of cervical nerve roots. We present this case with a review of reported cases of neurofibromatosis.
Key Words: Neurofibromatosis; Acoustic neurinoma; CPA meningioma; Ependymoma; Schwannoma
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