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Journal of Korean Neurosurgical Society 1995;24(2): 215-221.
A Case of Melanotic Neurofibroma Associated with Skull Defect in Neurofibromatosis.
Jung Yong Ahn, Jin Woo Chang, Joon Cho, Sang Sup Chung, Tai Seung Kim
Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea.
ABSTRACT
An unusual case of melanotic neurofibroma which involves subcutaneous tissue and dura in the occipital area is presented. The physical examination showed cutaneous pigmentation(cafe au lait spots) and multiple cutaneous tumors(fibroma molluscum). Magnetic resonance imaging showed plexiform neurofibroma and dural ectasia of typical finding of neurofibromatosis. The patient underwent surgical removal of the tumor as well as cranioplasty of the skull defect. The authors reviewed the literatures and discussed the pathogenesis of this extremely rare case.
Key Words: Neurofibromatosis; Skull defect; Melanotic neurofibroma; Pigmented neurofibroma
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