Malignant Fibrous Histiocytoma Presenting as Osteolytic Lesion on the Left Temporal Bone: A Case Report.

Yun, Li Gyu; Shin, Won Han; Kim, Bum Tae; Choi, Soon Kwan; Byun, Bark Jang; Lee, Dong Wha

Original Article

Journal of Korean Neurosurgical Society 1995;24(4): 471-476.

Li Gyu Yun, Won Han Shin, Bum Tae Kim, Soon Kwan Choi, Bark Jang Byun, Dong Wha Lee

¹Department of Neurosurgery, College of Medicine Soonchunhyang University, Seoul, Korea.
²Department of Anatoma Pathology, College of Medicine Soonchunhyang University, Seoul, Korea.

ABSTRACT

Malignant fibrous histiocytoma(MFH) is well known as a soft tissue tumor of the extremities and retroperitoneum, but MFH of the skull is very rare. We report a case of MFH arising from the temporal bone in a 27-year-old male. This tumor presented as an osteolytic lesion and soft tissue mass on the left temporal bone without obvious invasion of the underlying brain parenchyma. The patient underwent tumor and bone removal, follwed by radiation therapy. Hostologic examination disclosed pleomorphic spindle cells in a storiform pattern and tumor cells showed positive reaction for vimentin, lysozyme, alpha 1-antitrypsin and (1-antichymotrypsin in immunohistochemical stain.

Key Words: Malignant fibrous histiocytoma; Temporal bone; Osteolytic lesion; Immunohistochemical stain