| Home | E-Submission | Sitemap | Editorial Office |  
Journal of Korean Neurosurgical Society 1995;24(5): 497-504.
Development of Experimental 9L Gliosarcoma Rat Brain Tumor Model.
Jong Hyun Kim, Seung Hoon Lee, Chang Hun Rhe, Sang Min Yoon
Department of Neurosurgery, Korea Cancer Center Hospital, Seoul, Korea.
Experimental brain tumor model is essential for the development of new therapeutic modalities of brain tumors and evaluation of efficacy of each therapeutic variety. Authors developed experimental rat brain tumor model with 9L and C6 cell line in Fischer rat using stereotactic method. We tried to determine the tumor occurrence rate, the ideal time for secondary experiment using this brain tumor model, and the duration between the onset of neurological signs and the time of expiration. We performed autoradiography for each cell line to evaluate the reliance of the tumor model. We could make good tumor model in all the cases of experiment and except to use it in another extension of experiment.
Key Words: Brain tumor model; 9L gliosarcoma cell line; C6 glioblastoma cell line
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Related articles
Evaluation of 3-Dimensional Exoscopes in Brain Tumor Surgery  2021 March;64(2)
Models of Experimental Brain Tumors.  1984 June;13(2)
The Clinical Experience of Gliosarcoma(3 Cases).  1992 July;21(7)
Effect of Cyclosporin A in a Rat Spinal Cord Injury Model.  1998 October;27(10)
In Vivo Proton MR Spectroscopic Change of Experimental Rat Brain Abscess Model.  1999 October;28(10)
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: office@jkns.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer