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Journal of Korean Neurosurgical Society > Volume 24(12); 1995 > Article
Journal of Korean Neurosurgical Society 1995;24(12): 1530-1536.
Clinical Analysis of Pituitary Macroadenoma by Transsphenoidal Approach.
Jin Han Park, Oh Lyong Kim, Chan Youl Park, Seong Ho Kim, Jang Ho Bae, Byung Yon Choi, Soo Ho Cho
Department of Neurosurgery, School of Medicine, Yeungnam University, Taegu, Korea.
ABSTRACT
The authors report the results of transsphenoidal approach(TSA) for pituitary macroadenoma performd over a 2-year period.This series consisted of 15 patients:ten for nonfunctioning, two for prolactinoma, two of cushing's disease, one of acromegaly. The presenting symptom & sign was hyperfunctioning endocrinopathy in 5 patients, headache in 11 patients, visual symptom in 11 patients. TSA was performed without lumbar catheterization and fluoroscopic mornitoring. Success rates were as follows;normalization of endocrinopathy was achieved in 100% of cases;improvement of visual field in 100% of cases. There were no surgical mortality & some complication with three transient diabetes inspidus one hypopituitarysm. Eight of 15 patients who were removed tumor subtotally were received radiotherapy. Althrough there were short-term follow up(mean 19 months), there was no recurrence. This review reconfirms that the transspenoidal approach is safer and more effective procedure than craniotomy for pituitary macroadenomas.
Key Words: Pituitary macroadenoma; Transsphenoidal approach; Nonfunctioning; Radiotherapy
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