| Home | E-Submission | Sitemap | Editorial Office |  
top_img
Journal of Korean Neurosurgical Society 1996;25(7): 1489-1495.
Silent Corticotropic Adenomas of the Pituitary Gland: Cases Report.
Choong Hyun Kim, Young Il Ha
Department of Neurosurgery, Kangnam General Hospital, Public Corporation, Seoul, Korea.
ABSTRACT
This is our report of two cases of pituitary adenoma containing immunoreactive adrenocorticotropic hormone(ACTH) in tumor specimens but unassociated with Cushing's disease. The first case is a 39-year-old male with visual disturbance for 3 years. He was in a eucorticoid state clinically and biochemically. A large size pituitary tumor was found and removed by trans-sphenoidal approach. The tumor specimen was confirmed as adenoma with hematoxylin and eosin(H & E) staining;and immunohistochemical study demonstrated strong positivity for ACTH. The second case is a 61-year-old female with progressive deterioration of visual function and headache. She had no signs of symptoms of hormonal excess and was found to have a pituitary macroadenoma which was then removed by the trans-sphenoidal route. Surgical specimen also showed findings of adenoma;and immunohistochemical study revealed the presence of ACTH in biopsy. Since silent corticotropic adenoma of the pituitary gland is rarely encountered, the authors therefore report these 2 cases and causes of endocrinologic silence with review of literatures.
Key Words: Pituitary adenoma; Silent corticotropic adenoma; ACTH; Immunohistochemistry; Electron microscopy
TOOLS
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Share:      
METRICS
1,221
View
16
Download
Related articles
Intrathecal Herniation of Lumbar Disc: Case Report.  1974 June;3(1)
Chordoma in the Thoracic Spine: Case Report.  1974 October;3(2)
Chondroma of the Sphenoid Sinus: Case Report.  1975 June;4(1)
Hemangiopericytoma of the Brain:2 Case Report.  1975 June;4(1)
A Giant Cell Tumor of the Thoractic Vertebra: Case Report.  1975 October;4(2)
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: kns61@neurosurgery.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer