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Journal of Korean Neurosurgical Society 1997;26(4): 600-604.
Intracranial Meningeal Melanocytoma: Case Report.
Joon Sik Choi, Moo Seong Kim, Yong Tae Jung, Soo Chun Kim, Jae Hong Sim
Department of Neurosurgery, College of Medicine, Inje University, Paik Hospital, Pusan, Korea.
The majority of melanotic neoplasms of central nervous system(CNS) are metastatic in origin and rarely a primary CNS melanomas, and are usually histologically and clinically malignant in nature. The meningeal melanocytomas are benign, primary melanotic neoplasm and are less common than primary CNS melanoma. They usually present in early adult and have a characteristic appearance in light and electron microscope. A 42-year-old male is presented with pain on the neck and suboccipital region which was worse with flexion and Valsalva's maneuver. MRI revealed homogenous high signal intensity on the T 1 weighted image and low signal intensity on the T 2 weighted image. At operation, the tumor was well circumscribed, pigmented lesion and was attached to dura and cord. Microscopically, the tumor was composed of spindled and epithelioid cells with often prominent nucleoli, without evidence of mitosis and necrosis.
Key Words: Meningeal melanocytoma; Immunohistochemistry; Electron microscope; Magnetic resonance imaging; Surgical removal
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