|
|
Journal of Korean Neurosurgical Society 1997;26(6): 863-869. |
Probable Primary Leptomeningeal Melanoma: A Case Report. |
Hee Dae Kim, Seung Min Lee, Jae Yung Yang, Chun Sik Choi, Mun Bae Ju, Joo Seob Keum, Myung Suk Kim |
1Department of Neurosurgery, Kangbuk Samsung Hospital, College of Medicine Sung Kyun Kwan University, Seoul, Korea. 2Department of Pathology, Kangbuk Samsung Hospital, College of Medicine Sung Kyun Kwan University, Seoul, Korea. |
|
|
|
ABSTRACT |
Primary leptomeningeal melanomas(PLMs) are rare aggressive central nervous system(CNS) tumors without systemic foci. It can be very difficult, however, to clearly distinguish PLMs from those that have metastasized. We report a case of malignant leptomenigeal melanoma occurring in the right temporal convexity of a 77-yearold woman. Almost all malignant CNS melanomas in the old are secondary to the cutaneous melanoma and can cause diverse neurological manifestations; certain clinical findings of the presented case-namely, the patient's age, vague neurologic findings and absence of cutaneous lesions -are therefore interesting.
Thorough clinical checkups, including whole-body bone scan, whole spine MRI, abdominal ultrasound, and tumor marker studies to find extracranial lesions revealed no abnormalities. Based on these clinical findings, we suppose-though are not certain-that the tumor of the presented case is a PLM. |
Key Words:
Primary leptomeningeal melanoma; Malignant melanoma; Cutaneous melanoma |
|
|
|