Endodermal Sinus Tumor of the Scalp.

Oh, Sung Han; Whang, Kum; Pyen, Jin Soo; Hu, Chul; Hong, Soon Ki; Kim, Hun Joo; Han, Yong Pyo; Hong, Soon Won; Yang, Suk Woo

Case Report

Journal of Korean Neurosurgical Society 1997;26(11): 1599-1603.

Sung Han Oh, Kum Whang, Jin Soo Pyen, Chul Hu, Soon Ki Hong, Hun Joo Kim, Yong Pyo Han, Soon Won Hong, Suk Woo Yang

¹Department of Neurosurgery, Wonju College of Medicine, Yonsei University, Wonju, Korea.
²Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea.

ABSTRACT

Endodermal sinus tumors(yolk sac tumors) are malignant germ cell tumors that usually arise in the gonads. We report the first case, to our knowledge, of endodermal sinus tumor of the scalp. The tumor was present in a developmental infant with an abnormal scalp and exhibited histopathologic and immunohistochemical features identical to those of endodermal sinus tumors of gonadal origin. The tumor resolved after surgical excision and chemotherapy, and the patient is at present alive. The purpose of this report is to add a differential diagnosis to neoplasms of the scalp in neonates and review approaches to the management of this rare clinical entity.

Key Words: Germ cell tumor; Endodermal sinus tumor; Scalp; Combined chemotherapy