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Journal of Korean Neurosurgical Society 1997;26(12): 1635-1643. |
| Development of a System for Functional Mapping of the Human Brain Using 1.5-Tesla Magnet, and Its Applications. |
| Sung Hoon Chung, Jin Myung Jung, Sun Ha Paek, Tae Min Shin, Jae Hyoung Kim |
1Gyeongsang Institute for Neuroscience, Gyeongsang National University, Chinju, Korea.
2Department of Radiology, College of Medicine, Gyeongsang National University, Chinju, Korea.
3Department of Neurosurgery, College of Medicine, Gyeongsang National University, Chinju, Korea.
4Department of Electronic Engineering, College of Engineering, Gyeongsang National University, Chinju, Korea. |
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| ABSTRACT |
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Functional magnetic resonance imaging(fMRI) is a promising new imaging technique for functional mapping of cerebral cortex activation ; adequate image post-processing software is not readily available, however, we recently developed such a system based on the use of a personal computer, and evaluated its usefulness. With the cooperation of ten normal volunteers, 24 motor and five visual fMRIs activated by hand movement and photic stimulation, respectively, were performed on a 1.5-T MR unit using the gradient-echo technique(TR/TE/flip angle : 80/60/40degrees, 64X128 matrix). Functional maps were created by image post-processing, which consisted of subtraction, noise elimination by a statistical method, and coloration and overlapping of the images in sequence. All functional maps were successfully obtained. Twenty-four motor activation signals were detected in the sulci around the precentral gyrus, and five visual activation signals in the occipital lobes around the calcarine fissure. The image post-processing system developed in this study was useful for obtaining functional maps of human cerebral cortex activation. In conjunction with this system, fMRI can be successfully performed using a widely available 1.5-T MR unit. |
| Key Words:
Magnetic resonance(MR); Function; Activation; Brain; Blood flow |
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