| Home | E-Submission | Sitemap | Editorial Office |  
Journal of Korean Neurosurgical Society 1998;27(12): 1682-1686.
Treatment Strategy of Growth Hormone Secreting Pituitary Adenoma.
Gwon Ui Lew, Yoon Ha, Sun Ho Kim
Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
The goals of the pituitary tumor surgery are restoration of the normal pituitary function and relieving the mass effect on the adjacent normal brain structures. The main purpose of this study is to analyze our surgical results of growth hormone(GH) secreting pituitary adenomas which were treated extensive and aggressive surgical removal. The surgical results were reviewed in 36 patients treated between 1993 and 1997. The criteria of clinical remission are postoperative basal GH less than 5ng/ml and suppression of GH less than 2ng/ml in oral glucose tolerance test. As the results, 25 of 36 patients(69.4%) achieved surgical remission. Eleven patients who could not achieve remission by surgery were treated with medical treatment(octreotide, bromocriptine) and Gamma-knife surgery. In conclusion, the tumor morphology and extensiveness of tumor removal were well correlated with surgical outcome, and the aggressive resection of tumor seems to be the most important factor achieving remission in GH secreting pituitary adenomas.
Key Words: Growth hormone; Pituitary adenoma; Bromocriptine; Otreotide; Gamma-knife surgery
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Related articles
Clinical Analysis of Functiononing Pituitary Adenoma.  1982 December;11(4)
Analysis of Operative Results in Pituitary Adenoma.  1986 December;15(4)
Transsphenoidal Microsurgery of Pituitary Adenoma.  1988 April;17(2)
Neurosurgical Treatment of Giant Pituitary Adenoma.  1988 June;17(3)
Preoperative Bromocriptine Treatment of the Large Pituitary Adenoma.  1992 May;21(5)
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: office@jkns.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer