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Journal of Korean Neurosurgical Society 2001;30(2): 221-226.
A Case of Gliosarcoma Associated with Neurofibromatosis Type 1.
Dae Won Kim, Jong Tae Park, Jong Moon Kim, Tae Young Kim
Department of Neurosurgery, School of Medicine, Wonkwang University, Iksan, Korea.
A rare case of gliosarcoma with neurofibromatosis typeI is presented. The patient was a 33-year-old woman who had headache and vomiting for one week. Multiple neurofibromas over her whole body with many cafe-au-lait spots were present since childhood. At admission, she had no focal neurological deficit and ophthalmologic examination revealed bilateral Lisch nodules. Brain CT and MRI revealed a heterogeneously enhancing mass in the left fronto-parietal region with marked peritumoral edema and mass effect. The tumor was removed gross totally and a gliosarcoma was diagnosed histopathologically. Post operative course was uneventful with resolution of symptom, followed by radiotherapy with 60 Gy. A brief overview is given of this rare case together with the pertinent literature.
Key Words: Gliosarcoma; Neurofibromatosis type I
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