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Journal of Korean Neurosurgical Society 2001;30(12): 1430-1434.
A Case of Brain Abscess in a Patient with Primary Mucociliary Transport Failure.
Sung Hoon Yoon, Hyung Jin Lee, Jin Seok Yi, Ji Ho Yang, Il Woo Lee, Kyu Sang Song, Joon Ki Kang
1Department of Neurosurgery, The Catholic University, College of Medicine, Daejeon St. Mary's Hospital, Daejeon, Korea.
2Department of Anatomy, The Chungnam University, College of Medicine, Daejeon, Korea.
The authors present a case of brain abscess in a patient with primary mucociliary transport failure. Primary mucociliary transport failure is unfamiliar term to neurosurgeon. It encompasses three hereditary disorders, that is, primary ciliary dyskinesia, cystic fibrosis and Young's syndrome. Clinical manifestations in these disorders appear to overlap each other, e.g., male infertility and chronic sinopulmonary infections. These are characterized by ciliary dysfunction or abnormality of mucus secretion therefore recurrent infection occurs in organs containing the mucociliary transport system. Major causes of non-traumatic brain abscess are sinusitis and pulmonary infection. So the possibility of brain abscess is much higher if mucociliary transport failure exists. Especially, young patients who have brain abscess coexisting with chronic sinopulmonary infection should be considered primary mucociliary transport failure.
Key Words: Primary mucociliary transport failure; Brain abscess
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