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Journal of Korean Neurosurgical Society 2002;32(6): 599-602.
Atypical Teratoid/Rhabdoid Tumor in Central Nervous System: Report of 2 Cases.
Jae Myung Kim, Young Shin Ra, Thad T Ghim, Shin Kwang Khang
1Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. ysra@amc.seoul.kr
2Department of Pediatrics, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
3Department of Pathology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
ABSTRACT
We report two cases of atypical teratoid/rhabdoid tumor(AT/RT) in the central nervous system. Primary central nervous system AT/RT is an extremely rare malignant tumor affecting infants and young children. These tumors have been diagnosed previously as primitive neuroectodermal tumors(PNETs) because AT/RT contains fields indistinguishable from classic PNETs. Separation of these two tumor types is crucial because the prognosis for AT/RT is poor even when treatment includes surgery with or without radiation therapy and/or chemotherapy. Clinical, radiological and histopathological features of AT/RT are presented.
Key Words: Atypical teratoid/rhabdoid tumor; Surgery; Child; Chemotherapy
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