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Journal of Korean Neurosurgical Society 2003;33(2): 195-198.
Cerebral Central Neurocytoma with High Proliferative Index: Case Report.
Chi Heon Kim, Hee Won Jung, Sung Gyun Hwang, Je G Chi
1Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
2Department of Neuropathology, Seoul National University College of Medicine, Seoul, Korea.
3Neuroscience Institute, Medical Research Center, Seoul National University, Seoul, Korea.
ABSTRACT
We report a case of central neurocytoma that was located in the frontal lobe with high proliferative index. A 49-year old man was admitted complaining of a generalized seizure. On magnetic resonance imaging, a mass was detected in the right frontal and the preoperative radiological impression was oligodendroglioma. Light and electron microscopic with immunohistochemical examination revealed features of central neurocytoma. Radiotherapy was added because of the aggressive features of this tumor(Ki-67 labeling index 10%). Although cerebral central neurocytoma with a high proliferative index is rare and the long-term results of this tumors have not been studied, our case and other cases in the literatures suggest the need for postoperative radiotherapy.
Key Words: Central neurocytoma; Parenchyme; Ki-67
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