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Journal of Korean Neurosurgical Society 2004;35(3): 309-312.
Efficacy of Preoperative Chemotherapy in a Choroid Plexus Carcinoma.
Cheong Ho Noh, Jin Seok Yi, Hyung Jin Lee, Il Woo Lee
Department of Neurosurgery, The Catholic University, Daejeon St. Mary's Hospital, Daejeon, Korea. yijinseok@yahoo.co.kr
Choroid plexus carcinomas(CPCs) are rare neuroectodermal malginancies occuring mostly in young children of less than two years old, of which prognosis have been reported extremely grave. Generally, the extent of surgical resection has been regarded the most significant prognostic factor. However, the inherent hypervascularity and softness of these tumors make the total removal very difficult. We present our experience in a 18-months-old child with a large intraventricular CPC, of which total resection was achieved by the use of preoperative neoadjuvant chemotherapy with ICE regimen(Ifosfamide, Cisplatinum, Etoposide).
Key Words: Choroid plexus carcinoma; Hypervascularity; Neoadjuvant chemotherapy; Total resection; Prognostic facto
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