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Journal of Korean Neurosurgical Society 2004;35(3): 313-316. |
Malignant Variant of the Central Neurocytoma. |
Yu Seok Choi, Yeung Jin Song, Ki Yeong Huh, Ki Uk Kim |
1Department of Neurosurgery, College of Medicine, Dong-A University, Busan, Korea. kukim@mail.donga.ac.kr 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea. |
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ABSTRACT |
Central neurocytoma is a rare, well-differentiated neuronal tumor and is usually located in the lateral or third ventricle of young adults. Its overall prognosis is excellent with a low proliferative index. The majority of previously reported malignant variants rarely did recurred after tumor removal and regarded as benign tumor despite of histopathological malignant feature. Nevertheless, we experienced a case of malignant variant of the central neurocytoma with high proliferative index(Ki-67 labeling index >30%), which showed recurrence immediately after surgery and died within 3 months POD. Here, we describe the case with a review of the literatures. |
Key Words:
Central neurocytoma; Recurrence; Ki-67 labeling index |
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