| Home | E-Submission | Sitemap | Editorial Office |  
top_img
Journal of Korean Neurosurgical Society 2004;35(4): 393-400.
A Clinical Analysis of Anaplastic Oligodendroglioma.
Jong Sool Kang, Kyu Jeong Kim, Bumn Suk Suh, Jong Soo Lee, Hyun Sung Lee
Department of Neurosurgery, Sun Hospital, Daejeon, Korea. hslee@sunhospital.com
ABSTRACT
OBJECTIVE
The author evaluate the efficacy of surgery, radiation therapy and chemotherapy as a treatment methods for anaplastic oligodendroglioma patients to provide the standardized treatment option. METHODS: A retrospective analysis of ten pathologically proven cases of anaplastic oligodendroglioma was performed. RESULTS: The ten patients comprised four males and six females. The mean age at diagnosis was 34.4 year (8-70). The mean follow-up was 40.5 months, and two patients died of tumor progression during the follow-up (70, 86 months, respectively). All patients had craniotomy and the tumors were removed as much as possible. The tumos were resected totally in five cases, only subtotally in the rest. Radiation therapy was applied to seven patients, and PCV (procarbazine-CCNU-vincristine) based chemotherapeutic agent was administered to five patients. In the group with PCV therapy, complete remission was observed in two, partial remission was in one, stable disease in one, and disease progression in one who were died of tumor extension. During the follow-up, tumor recurrences were observed in four patients, and they were treated with additional operation and/or chemotherapy. CONCLUSION: Anaplastic oligodendrogliomas respond to the surgical and radiological treatment and especially to the chemotherapy, and have a relatively good prognosis. PCV is an effective and safe regimen for suppressing tumor growth, and is feasible for recurrent cases. PCV chemotherapy should be considered for primary treatment method for anaplastic oligodendroglioma patients.
Key Words: Anaplastic oligodendroglioma; Radiation therapy; Chemotherapy; PCV
TOOLS
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Share:      
METRICS
1,283
View
74
Download
Related articles
A Clinical Study of Sellar and Parasellar Lesions.  1973 October;2(2)
A Clinical Study on Cranioplasty.  1974 October;3(2)
A Case of Oligodendroglioma.  1974 October;3(2)
Clinical Analysis of Intracerebral Hematoma.  1975 October;4(2)
A Case of Oligodendroglioma.  1976 June;5(1)
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: office@jkns.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer