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Journal of Korean Neurosurgical Society 2004;36(4): 324-327.
Malignant Giant Cell Tumor of the Skull.
Sang Won Hong, Ha Young Choi
Department of Neurosurgery, Research Institute for Clinical Medicine, Chonbuk National University Medical School Hospital, Jeonju, Korea. hayoungc@moak.chonbuk.ac.kr
ABSTRACT
Giant cell tumor(GCT) is a rare primary bone tumor that seldom involves the skull. Malignant change in the GCT series also develops on rare occasions, but when it does, it most commonly occurs several years after radiation therapy. Furthermore, the malignant change from benign GCT without radiation therapy is extremely rare. The authors present a case of primary malignant GCT that received no previous radiation therapy and that arose from multiple areas of the skull, predominantly in the parieto-occipital region.
Key Words: Giant cell tumors; Skull
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