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Journal of Korean Neurosurgical Society 2004;36(4): 334-336.
Coexistence of Cerebral Amyloid Angiopathy and an Arteriovenous Malformation in a Young Adult.
Suk Hyung Kang, Jong Sik Suk, Byung Kook Min, Jeong Taik Kwon
Department of Neurosurgery, College of Medicine, Chung-Ang University, Seoul, Korea. nscharisma@hanmail.net
ABSTRACT
The prevalence and cerebral hemorrhage of cerebral amyloid angiopathy(CAA) are age-related. It is rare in young adults. The authors report on CAA coexisting with an arteriovenous malformation(AVM) in a 30-year-old male, who present with the sudden onset of headache and vomiting. Magnetic resonance imaging revealed a cerebral hemorrhage with an AVM. The AVM was completely removed through the hematoma and the histological section obtained from the periphery of the hematoma showed the typical findings of CAA. The epsilon4 allele of apoprotein E(apoE) was identified in genotype determination.
Key Words: Cerebral amyloid angiopathy; Arteriovenous malformation; Cerebral hemorrhage; ApoE; Pathology
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