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Journal of Korean Neurosurgical Society 2006;39(1): 64-67.
Intracranial Solitary Fibrous Tumor.
Jun Won Jang, Chang Hyun Kim, Chong Woo Yoo, Jae Gon Moon
1Department of Neurosurgery, University of Hallym College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Korea. nskch@nuri.net
2Department of Pathology, University of Hallym College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Korea.
Solitary fibrous tumor is a spindle cell neoplasm that can arise in any place of the body. Intracranial solitary fibrous tumors are rare. To our knowledge, only 57 cases with intracranial lesion have been reported. In Korea three cases have been reported. Our case was a 23-year-old woman who presented with morning headache. MRI showed a large intra-axial mass involving falx with typically isointense and heterogeneous strong enhancement on T1 weighted image in the right parieto-occipital region. Histologically the tumor showed spindle shaped cells within matrix with thick collagen deposition, hypercellularity, focal necrosis, and pleomorphism. Immunohistochemical study demonstrated diffuse positivity for CD34, Vimentin, Reticulin. In case of the intracranial tumors involving the meninges, we also should consider the solitary fibrous tumor with immunohistochemical staining for accurate diagnosis.
Key Words: Solitary fibrous tumor; CD34; Intracranial
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