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Journal of Korean Neurosurgical Society 2006;39(4): 303-305.
Rosai-Dorfman Disease in Posterior Fossa.
Sang Ha Shin, Jhin Soo Pyen, Chul Hu, Mee Yon Cho
1Department of Neurosurgery, Yonsei University, Wonju College of Medicine, Wonju, Korea. pjs0311@hanmail.net
2Department of Pathology, Yonsei University, Wonju College of Medicine, Wonju, Korea.
Rosai-Dorfman Disease(RDD) is an idiopathic histiocytic proliferation affecting lymph nodes. Although extranodal involvement has been reported in the skin, orbit, upper respiratory tract, or testes, the isolated intracranial involvement without associated lymphadenopathy is extremely rare. We report our experience with 1 case of an isolated intracranial RDD without associated lymphadenopathy and any other organ involvement. A 61-year-old male presented with an isolated well-circumscribed brain mass in the posterior fossa, preoperatively thought to be a meningioma. But histology and immunohistochemistry confirmed that the lesion was RDD.
Key Words: Idiopathic histiocytosis without lymphadenopathy; Rosai-Dorfman disease
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