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Journal of Korean Neurosurgical Society > Volume 41(4); 2007 > Article
Journal of Korean Neurosurgical Society 2007;41(4): 217-223.
doi: https://doi.org/10.3340/jkns.2007.41.4.217
Therapeutic Strategies of the Intracranial Meningioma in Elderly Patients.
Young Jin Song, Soon Ki Sung, Seung Jin Noh, Hyung Dong Kim
Department of Neurosurgery, Dong-A University College of Medicine, Busan, Korea. hdkim@donga.ac.kr
ABSTRACT
OBJECTIVE:
The apparent increase in the incidence of the intracranial meningiomas in the elderly is due in part to improved diagnostic tools and improved span of life. The authors carried out a retrospective study to validate the use of the Clinical-Radiological Grading System (CRGS) as a clinical tool to orientate surgical decision making in elderly patients and to explore prognostic factors of survival.
METHODS:
From January 1997 to January 2006, the authors consecutively recruited and surgically treated 20 patients older than 65 years of age with radiologic findings of intracranial meningiomas and a preoperative evaluation based on the CRGS.
RESULTS:
High CRGS score was associated with a higher probability of good outcome (p=0.004) and a lower probability of postoperative complications (p=0.049). Among the different subset items of the CRGS score, larger maximum tumor diameters (D> or =4cm) and the presence of a severe peritumoral edema were associated with incidence rate of postoperative poor outcome and complications (p<0.05). Additionally, the critical location of the tumor was also correlated with poor outcome (p<0.05).
CONCLUSION:
A CRGS score higher than 13 is a good prognostic indication of survival. The CRGS score is a useful and practical tool for the selection of elderly patients affected by intracranial meningiomas as surgical candidates.
Key Words: Intracranial meningioma; CRGS; Elderly patients; Prognosis
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