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Journal of Korean Neurosurgical Society 2007;41(6): 408-410. |
Paradoxical Deterioration of Intramedullary Spinal Tuberculomas during Antituberculous Therapy. |
Keum Jun Jang, Cheol Su Jwa, Kang Hyun Kim, Jae Kyu Kang |
Department of Neurosurgery, National Medical Center, Seoul, Korea. chsjwa@hanmail.net |
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ABSTRACT |
"Paradoxical deterioration" during antituberculous therapy is generally defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. The phenomenon of paradoxical deterioration in intramedullary tuberculoma of the spinal cord is rare and is a less established entity. The authors present an unusual case of paraparesis as a result of paradoxical deterioration of intramedullary tuberculoma despite adequate antituberculous therapy. Here, we review the relevant literatures and discuss its possible pathogenic mechanisms. |
Key Words:
Tuberculoma; Spinal cord; Antituberculous therapy |
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