| Home | E-Submission | Sitemap | Editorial Office |  
top_img
Journal of Korean Neurosurgical Society > Volume 43(1); 2008 > Article
Journal of Korean Neurosurgical Society 2008;43(1): 26-30.
doi: https://doi.org/10.3340/jkns.2008.43.1.26
Development of a Stereotactic Device for Gamma Knife Irradiation of Small Animals.
Hyun Tai Chung, Young Seob Chung, Dong Gyu Kim, Sun Ha Paek, Keun Tae Cho
1Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea. yschung@snu.ac.kr
2Department of Neurosurgery, Dongguk University International Hospital, Goyang, Korea.
ABSTRACT
OBJECTIVE:
The authors developed a stereotactic device for irradiation of small animals with Leksell Gamma Knife(R) Model C. Development and verification procedures were described in this article.
METHODS:
The device was designed to satisfy three requirements. The mechanical accuracy in positioning was to be managed within 0.5 mm. The strength of the device and structure were to be compromised to provide enough strength to hold a small animal during irradiation and to interfere the gamma ray beam as little as possible. The device was to be used in combination with the Leksell G-frame(R) and KOPF(R) rat adaptor. The irradiation point was determined by separate imaging sequences such as plain X-ray images.
RESULTS:
The absolute dose rate with the device in a Leksell Gamma Knife was 3.7% less than the value calculated from Leksell Gamma Plan(R). The dose distributions measured with GAFCHROMIC(R) MD-55 film corresponded to those of Leksell Gamma Plan(R) within acceptable range. The device was used in a series of rat experiments with a 4 mm helmet of Leksell Gamma Knife.
CONCLUSION:
A stereotactic device for irradiation of small animals with Leksell Gamma Knife Model C has been developed so that it fulfilled above requirements. Absorbed dose and dose distribution at the center of a Gamma Knife helmet are in acceptable ranges. The device provides enough accuracy for stereotactic irradiation with acceptable practicality.
Key Words: Stereotactic device; Gamma Knife Model C; Absolute dose; Dose distribution
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
2
Crossref
0
Scopus
1,189
View
5
Download
Related article
A Stereotactic Device for Gamma Knife Irradiation to Cell Lines.  2004 June;35(6)
Editorial Office
#402, 27 Chilparo, Jung-gu, Seoul 04511, Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: kns61@neurosurgery.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society. All rights reserved.                 Developed in M2PI
Close layer
prev next