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Journal of Korean Neurosurgical Society 2011;49(2): 112-115.
doi: https://doi.org/10.3340/jkns.2011.49.2.112
Vasogenic Edema of the Basal Ganglia after Intra-Arterial Administration of Nimodipine for Treatment of Vasospasm.
Chang Woo Ryu, Jun Seok Koh, Seung Young Yu, Eui Jong Kim
1Department of Radiology, Stroke and Neurological Disorders Centre, East-West Neo Medical Hospital, Kyung Hee University School of Medicine, Seoul, Korea.
2Department of Neurosurgery, Stroke and Neurological Disorders Centre, East-West Neo Medical Hospital, Kyung Hee University School of Medicine, Seoul, Korea. neurokoh@hanmail.net
3Department of Ophthalmology, Medical Center, Kyung Hee University School of Medicine, Seoul, Korea.
4Department of Radiology, Medical Center, Kyung Hee University School of Medicine, Seoul, Korea.
ABSTRACT
The intra-arterial administration of nimodipine (IAN) is commonly used for cerebral vasospasm refractory to medical treatments. We report two cases of vasogenic edema after IAN. Our patients with aneurismal subarachnoid hemorrhage presented with vasospasm, which was treated by IAN. Consequently, vasogenic edema developed in the basal ganglia. Reperfusion following IAN for vasospasm may have the potential for inciting vasogenic edema in the ischemic brain.
Key Words: Brain edema; Chemical angioplasty; Nimodipine; Vasospasm
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