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Journal of Korean Neurosurgical Society > Volume 61(2); 2018 > Article
Erratum to “Retrospective Analysis of Cerebrospinal Fluid Profiles in 228 Patients with Leptomeningeal Carcinomatosis : Differences According to the Sampling Site, Symptoms, and Systemic Factors” by Shim Y, et al. (J Korean Neurosurg Soc 59 : 570-576, 2016)
In this article by Shim et al., the measurement unit of CSF cell count was given incorrectly. It should be “cells/mm3” instead of “cells/cm3”.
Corrected sentences are as follows;
Page 570 Results of abstract :
Cell counts (median : 8 vs. 1 cells/mm3) and protein levels (median : 68 vs. 17 mg/dL) significantly higher in lumbar CSF than in ventricular CSF (p<0.001).
Page 571 (right column), line 46-53 :
The mean total cell count in the lumbar CSF was 25.0 cells/mm3 (standard deviation : ±47.3; range : 0-310). The reference normal range was set at ≤5 cells/mm3. The distribution of the cell count had a leftward skew (median : 8 cells/mm3; third quartile : 25 cells/mm3) (Fig. 1A). The distribution of the cell counts in the ventricular CSF was also skewed (mean : 10.4 cells/mm3; standard deviation : ±44.2; range : 0-360; median : 1 cells/mm3; third quartile : 5 cells/mm3) (Fig. 1B).
Page 573 (left column) line 5 :
(median: 2 vs. 9 cells/mm3; p=0.046).
Page 574 (right column) line 1-2 :
the ventricular CSF (1 cell/mm3) was within the normal range and that 75% of the patients had ≤5 cells/mm3.
Page 574 Table 2 :
Table 2
Lumbar and ventricular CSF profiles correlated with LMC symptoms (n=228)
LMC symptoms Lumbar CSF profiles Ventricular CSF profiles


Cell count (cells/mm3) p value Protein (mg/dL) p value Cell count (cells/mm3) p value Protein (mg/dL) p value CEA (n=109) p value
Increased ICP (15 mm Hg) 0.57 0.34 0.47 0.50 0.40
 Yes (n=129) 7 (0-300) 75.5 (17-703) 1 (0-360) 18.5 (7-223) 53 (0-5098)
 No (n=99) 8 (0-205) 63 (17-1246) 1 (0-180) 17 (6-885) 13 (0-2822)
Hydrocephalus 0.62 0.049 0.58 0.15 0.01
 Yes (n=59) 9 (0-100) 92.5 (25-1064) 1 (0-180) 19 (6-885) 96 (0-4057)
 No (n=169) 8 (0-300) 61 (17-1246) 1 (0-360) 16 (6-237) 12 (0-5098)
Cauda equina syndrome 0.45 <0.001 0.34 0.11 0.56
 Yes (n=54) 8 (0-282) 118 (35-1246) 0 (0-90) 19 (6-114) 25.3 (0-4057)
 No (n=174) 8 (0-300) 59 (17-889) 1 (0-360) 16 (6-885) 15 (0-5098)
Cranial neuropathy 0.046 0.54 0.16 0.44
 Yes (n=23) 2 (0-175) 68 (17-1246) 0 (0-79) 0.16 16 (8-237) 0.44 8(0-2822) 0.72
 No (n=205) 9 (0-300) 61 (21-570) 1 (0-360) 17 (6-885) 20.8 (0-5098)

Representative numbers are median value and numbers in the parenthesis are ranges of observed values. CSF : cerebrospinal fluid, LMC : leptomeningeal carcinomatosis, ICP : intracranial pressure, CEA : carcinoembryonic antigen

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