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Journal of Korean Neurosurgical Society > Volume 48(6); 2010 > Article
Journal of Korean Neurosurgical Society 2010;48(6): 524-527.
doi: https://doi.org/10.3340/jkns.2010.48.6.524
Transient Global Aphasia with Hemiparesis Following Cerebral Angiography : Relationship to Blood Brain Barrier Disruption.
Dong Ha Kim, Chang Hwa Choi, Jung Hwan Lee, Jae Il Lee
Department of Neurosurgery, Pusan Cancer Center, School of Medicine, Pusan National University, Busan, Korea. chwachoi@pusan.ac.kr
Temporary disruption of the blood-brain barrier (BBB) after cerebral angiography is presumably caused by nonionic radiographic contrast medium (CM). We hereby report a case of 58-year-old woman who developed decreased mentality, global aphasia and aggravated right hemiparesis after cerebral angiography. Brain CT examination demonstrated gyriform enhancement throughout the left cerebral cortex and thalamus. MR diffusion did not reveal acute infarction. MR angiography did not show any stenosis, spasm or occlusion at the major cerebral vessels. Follow-up CT scan after 1 day did not show any gyriform enhancement. Worsened neurologic signs and symptoms were improved completely after 7 days. In the present study, disruption of the BBB with contrast medium after angiography seems to be the causative factor of transient neurologic deterioration.
Key Words: Blood brain barrier (BBB) disruption; Contrast medium; Transient global aphasia; Transient hemiparesis; Cerebral angiography
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